Skin concern

Volume Loss

Volume loss is a structural change: fat pads thin, bone remodels and collagen reduces with age. Medical-grade intervention can restore what has been lost without changing fundamental facial anatomy.

Understanding the cause

What's happening in your skin

01

Every layer changes simultaneously

From the mid-twenties, fat pads thin, bone remodels and collagen reduces all at once. The folds and hollows you see on the surface reflect structural changes underneath, not a skin problem.

Facial volume is maintained by a scaffold of fat compartments, bone, muscle and connective tissue. From the mid-twenties, every layer changes simultaneously. Fat pads thin and descend. Bone at the orbital rim and jaw remodels to occupy a smaller surface area. Collagen and elastin reduce throughout the dermis. The result is predictable: cheeks flatten, undereye hollows deepen, the jawline loses definition and the skin loses its structural support.

02

Surface treatment before structure limits results

A nasolabial fold often reflects midface descent. Restoring the volume above frequently improves the fold without touching it directly.

The intuitive response to a fold is to fill it directly. Most visible folds are secondary to structural changes in the deeper layers. A nasolabial fold may respond significantly better to restoring the midface volume that has descended than to treating the fold itself. Adding volume at the surface without addressing the underlying scaffold produces a result that looks less natural and metabolises faster.

03

A structured approach to restoration

Dr Shahe Boghossian supports deep scaffolding first, then mid-layer volume, then surface skin quality. This sequence produces results that integrate naturally and last longer.

Dr Shahe Boghossian, who leads injectable treatment at the clinic, approaches volume restoration in a deliberate sequence: deep scaffolding first, then mid-layer volume, then surface skin quality. This layered approach produces results that integrate naturally with existing facial anatomy. Dermal fillers provide structural lift at the appropriate depths. Profhilo and polynucleotides improve skin quality above. A thorough facial assessment determines which layers need attention and in what order.

Recommended treatments

What we use for volume loss

Clinical perspective

Volume loss is where I see the biggest difference between treating the symptom and treating the cause. A deep nasolabial fold looks like it needs filler in the fold, but if you address the midface volume deficit that is allowing the cheek to descend, the fold often improves significantly without touching it directly. Results that look natural and last are almost always about restoring structure rather than filling in wrinkles.

Treat structure, not folds Less is more Natural and lasting results
Lydia Griffin, Clinic Director, The London Road Clinic

In their own words

Dr. Boghossian is very professional, with a very light touch. I been in different clinics but the pain I use to feel is unbearable. I will keep coming to your clinic for more treatments.
Sheila · with Dr Shahe Boghossian, Medical Consultant · May 2026

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Common questions

Frequently asked about volume loss

Which areas can be treated for volume loss?
The most commonly treated areas are the cheeks, temples, undereye hollows (tear troughs), jawline and chin. Lips lose volume with age and can be subtly restored. Treatment is always approached holistically, addressing the structural layers that provide the most support before moving to surface refinement.
Is volume restoration with fillers safe?
Dermal fillers are medical procedures that carry real risks including bruising, swelling, infection and, in rare cases, vascular complications. At The London Road Clinic, all injectable treatments are carried out by experienced practitioners following thorough consultation, detailed facial assessment and in accordance with current GMC, NMC and GPhC guidance. Risks and aftercare are always discussed before any treatment begins.
How much filler will I need?
This depends on the degree of volume loss and the areas being treated. A meaningful aesthetic change typically requires 1–3ml across multiple areas, though some people start with a single area and reassess. Your clinician will give you a clear volume recommendation based on your facial assessment, not on a menu.
How long does volume restoration last?
HA filler longevity depends on the product formulation and the area treated. Structural areas such as the cheeks typically retain filler for twelve to twenty-four months. Areas with more movement, such as the lips, metabolise filler more quickly at six to twelve months. Profhilo and polynucleotides produce quality improvements that build over weeks and typically last six to twelve months.
Can volume be restored without injectables?
Non-injectable options, skin boosters, microneedling, radiofrequency, can improve skin quality, hydration and firmness, which contributes to a fuller appearance. They cannot replace lost structural volume. For people with significant volume deficit, injectables produce results that biostimulators and resurfacing cannot match alone.

Ready to take the next step?

Book a consultation

Your clinician will assess your skin, review your history and design a treatment plan matched to your specific presentation, not a generic protocol.

Medically reviewed by Dr Shahe Boghossian, Medical Consultant, GMC 5204600 . Last reviewed 21 May 2026.

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