Injectable treatment

Polynucleotides in Newark

A consultation-led regenerative injectable for fine lines, crepey texture and loss of firmness, especially in delicate areas such as the eye area and mid-face.

Polynucleotides at The London Road Clinic, Newark
Price
From £195 per session with Lydia, £250 with Mel or Dr Shahe. Course of three with Mel or Dr Shahe, £600
Duration
30 mins
Downtime
Usually minimal. Temporary swelling, redness or small injection-site marks can occur and usually settle quickly.
Results
Results tend to build gradually over several weeks as skin quality improves

The treatment

How Polynucleotides works

Polynucleotides are purified nucleic-acid fragments used in regenerative injectable treatments. Unlike dermal filler, they do not add volume or change facial shape. Instead, they work over time to support skin repair processes, improve hydration and build elasticity. At The London Road Clinic they are particularly used for fine lines, crepey texture and reduced firmness in delicate areas such as the eye area and mid-face.

What patients notice

What to expect

  • Supports skin repair and regeneration
  • Improves hydration and elasticity over time
  • Suitable for delicate areas where filler may not be the right fit
  • No volumising effect
  • Builds gradual, natural-looking improvement

Before you book

Is this treatment right for you?

Suitable for

  • Adults who want skin-quality improvement for fine lines, crepey texture or reduced firmness, particularly in delicate facial areas.

Not suitable for

  • Suitability must be checked in consultation. Treatment may not be appropriate during pregnancy or breastfeeding, with active skin infection or where there are other medical contraindications to injectable treatment.

In their own words

Every visit to London Road Clinic is wonderful, all the staff make you feel comfortable & relaxed. I’ve recently had a course of three Polynucleotide for my face. I was nervous & uncertain however Lydia gave me 100% confidence in her knowledge & experience which gave me complete trust in her.. The results in my skin are already showing… plumper, fewer deep lines and added radiance. Ageing is a privilege not given to everyone but in a world where we all strive to look our best, this treatment works wonders, the salmon DNA stimulates cell regeneration, collagen and elastin production. 100%
Mandy · with Lydia · 2 Sep 2025

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After your appointment

Aftercare

Keep skincare gentle, use SPF and avoid heat, heavy exercise and excessive touching of the area for the period advised by your clinician. Follow all injectable aftercare guidance.

What they will not do

People arrive asking for polynucleotides because they have read they are the alternative to filler, which is half right. They do not add volume and they will not change the shape of your face, so if that is what you want you should have a different conversation. What they do is work on the quality of the skin itself, over a course. The people happiest with them wanted their skin to behave better rather than look different.

Lydia Griffin, Clinic Director

Two or three visits, a few weeks apart

The clinic is at 65 London Road, Newark-on-Trent, NG24 1RZ, with free parking at the front.

A short course, often around two to three sessions, spaced a few weeks apart. That is a manageable number of trips even from the edge of the county, and it is the whole commitment rather than the start of one.

The clinic is a short drive from Southwell, Bingham, Tuxford and Collingham, and the A1 and A46 bring West Bridgford, Keyworth, Lincoln, Grantham and Nettleham within range.

Small bumps at the injection points and some redness are expected on the day and settle. Under the eyes they are more visible than elsewhere, so plan the evening accordingly.

Further reading: the patient guide to polynucleotides, and how Profhilo, polynucleotides and skin boosters compare. Background on the concerns: under-eye concerns and fine lines and wrinkles.

If the drive is the question, we have written it up for Mansfield and for Southwell.

Common questions

Frequently asked about Polynucleotides

What do polynucleotides treat?
The clinic positions them for concerns such as fine lines, crepey texture and loss of firmness, especially around delicate areas such as the eye area or mid-face.
How do polynucleotides work?
They use purified nucleic-acid fragments to support skin repair processes, hydration and elasticity over time rather than changing facial shape.
Are polynucleotides the same as filler?
No. The clinic explains that they do not add bulk like filler and are used instead for regenerative skin-quality support.
Which areas are commonly treated?
The live treatment page particularly highlights delicate areas such as around the eyes and mid-face.
How many sessions are usually needed?
A short course is usually recommended, often around 2 to 3 sessions depending on the treatment plan.
When will I see results?
Results usually build gradually over several weeks as skin quality, hydration and firmness improve.
Is there downtime after treatment?
Downtime is usually minimal, although temporary redness, swelling or small injection-site marks can occur.
Who may not be suitable for treatment?
As with other injectable treatments, suitability needs clinician review, especially in pregnancy or breastfeeding, with active skin infection or with other medical contraindications.

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Medically reviewed by Dr Shahe Boghossian, Medical Consultant, GMC 5204600. Last reviewed 6 Aug 2026. Page updated 16 Aug 2026.

65 London Road, Newark

Ready to find out more?

Your clinician will take the time to understand your concerns, assess your skin and talk through what Polynucleotides could realistically achieve for you. No obligation to proceed.

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