Injectables
Platelet Rich Plasma (PRP)
- Duration
- 60 mins
- Downtime
- Mild redness is possible for around 1 to 3 days, with temporary bruise or swelling risk at injection or needling sites
From £150
Injectable treatment
Polynucleotides in Newark
A consultation-led regenerative injectable for fine lines, crepey texture and loss of firmness, especially in delicate areas such as the eye area and mid-face.
- Price
- From £200
- Duration
- 30 mins
- Downtime
- Usually minimal. Temporary swelling, redness or small injection-site marks can occur and usually settle quickly.
- Results
- Results tend to build gradually over several weeks as skin quality improves
- Longevity
- Varies by skin condition, treatment area and whether maintenance sessions are used
The treatment
How Polynucleotides works
Polynucleotides are purified nucleic-acid fragments used in regenerative injectable treatments. Unlike dermal filler, they do not add volume or change facial shape. Instead, they work over time to support skin repair processes, improve hydration and build elasticity. At The London Road Clinic they are particularly used for fine lines, crepey texture and reduced firmness in delicate areas such as the eye area and mid-face.
What patients notice
What to expect
- Supports skin repair and regeneration
- Improves hydration and elasticity over time
- Suitable for delicate areas where filler may not be the right fit
- No volumising effect
- Builds gradual, natural-looking improvement
Before you book
Is this treatment right for you?
Suitable for
- Adults who want skin-quality improvement for fine lines, crepey texture or reduced firmness, particularly in delicate facial areas.
Not suitable for
- Suitability must be checked in consultation. Treatment may not be appropriate during pregnancy or breastfeeding, with active skin infection or where there are other medical contraindications to injectable treatment.
In their own words
"My under-eyes were the thing that bothered me most. Polynucleotides have made a visible difference to the texture and I never felt the results were overdone." (Representative client experience. Individual results vary.)
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After your appointment
Aftercare
Keep skincare gentle, use SPF and avoid heat, heavy exercise and excessive touching of the area for the period advised by your clinician. Follow all injectable aftercare guidance.
Common questions
Frequently asked about polynucleotides
What do polynucleotides treat?
The clinic positions them for concerns such as fine lines, crepey texture and loss of firmness, especially around delicate areas such as the eye area or mid-face.
How do polynucleotides work?
They use purified nucleic-acid fragments to support skin repair processes, hydration and elasticity over time rather than changing facial shape.
Are polynucleotides the same as filler?
No. The clinic explains that they do not add bulk like filler and are used instead for regenerative skin-quality support.
Which areas are commonly treated?
The live treatment page particularly highlights delicate areas such as around the eyes and mid-face.
How many sessions are usually needed?
A short course is usually recommended, often around 2 to 3 sessions depending on the treatment plan.
When will I see results?
Results usually build gradually over several weeks as skin quality, hydration and firmness improve.
Is there downtime after treatment?
Downtime is usually minimal, although temporary redness, swelling or small injection-site marks can occur.
Who may not be suitable for treatment?
As with other injectable treatments, suitability needs clinician review, especially in pregnancy or breastfeeding, with active skin infection or with other medical contraindications.
You may also want to explore
Related treatments
Skin
Exosome Therapy
- Duration
- 60 mins
- Downtime
- Minimal. If combined with microneedling, mild redness is common and usually settles quickly.
From £450
Injectables
Profhilo Skin Booster
- Duration
- 30 mins
- Downtime
- Usually minimal. Small bumps, redness or mild tenderness can occur temporarily after treatment.
From £170
65 London Road, Newark
Ready to find out more?
Your clinician will take the time to understand your concerns, assess your skin and talk through what Polynucleotides could realistically achieve for you. No obligation to proceed.
Reviewed by Lydia Griffin, Clinic Director, JCCP No. 002569 . Last updated 21 May 2026.
