Treatment comparison
Profhilo Skin Booster vs Dermal Fillers
Profhilo vs dermal filler at The London Road Clinic, Newark. Understand the clinical difference between these two hyaluronic acid injectables and which is right for your concern.
Side by side
At a glance
| Compare | Profhilo Skin Booster | Dermal Fillers |
|---|---|---|
| Product type | High-concentration hyaluronic acid spread across specific bio-remodelling points | Hyaluronic acid gel placed precisely into targeted anatomical areas |
| Primary effect | Improves skin quality, hydration and elasticity across the treated area | Restores volume, supports structure and refines contour in specific zones |
| Changes facial shape | No | Yes, in the areas treated |
| Best for | Crepey, dull or lax skin where the goal is overall quality and resilience | Volume loss, contour imbalance or etched lines in specific areas such as lips, cheeks, chin or jawline |
| Sessions needed | 2 sessions, typically 4 weeks apart | Often a single session; staged treatment where appropriate |
| Downtime | Usually minimal; small injection bumps settle quickly | Usually mild; swelling and tenderness settle over 24 to 48 hours |
| Results timeline | Builds gradually over several weeks | Immediate, with settling and refinement over 1 to 2 weeks |
| Reversibility | HA breaks down naturally over time | HA fillers can be dissolved with hyaluronidase if clinically needed |
| Price from | From £170 | From £240 |
The science
How each treatment works
Profhilo Skin Booster
Profhilo uses high-concentration hyaluronic acid placed in specific bio-remodelling points on the face, neck or hands. Rather than sculpting or adding bulk, the aim is to spread hydration, improve elasticity and rebuild overall skin quality over time. It works especially well for skin that feels crepey, dull or less resilient rather than primarily volume-depleted.
Full Profhilo Skin Booster details →Dermal Fillers
Hyaluronic acid filler is placed precisely into targeted areas of the face to restore volume, support structure and refine contour. HA also attracts water within the tissue, adding a subtle freshness. Product choice, depth and technique are always tailored to the specific area and the result discussed in consultation.
Full Dermal Fillers details →Clinical perspective
Which is right for you?
Skin quality vs volume: these are not the same concern
Profhilo improves the quality of your skin. Dermal filler replaces structural volume. Both use hyaluronic acid, but they are designed for different problems and should not be treated as alternatives to each other.
Profhilo is a skin-quality treatment. High-concentration HA is placed at specific bio-remodelling points and is designed to spread through the tissue, improving hydration, elasticity and skin resilience across the treated area. It does not add volume or change the shape of the face. The result is skin that looks and feels more hydrated and more resilient. Dermal fillers work differently: they are placed precisely into specific anatomical zones to restore structure, refine contour or replace lost volume. Results are immediate. Fuller cheeks, a more defined jawline, smoother folds, or restored lip volume are visible on the day of treatment, settling and refining over the following week or two.
Your concern determines which is appropriate
Crepey, dull or lax skin points toward Profhilo. Volume loss, visible folds or contour changes in a specific area point toward filler.
Choosing the wrong treatment for the right patient produces no useful result. If the concern is the quality and tone of the skin itself, Profhilo is the more targeted starting point. If the concern is visible hollowing, facial flattening or a specific structural change you want to address in a defined area, filler is the appropriate intervention. Your clinician will clarify which mechanism is driving what you see before recommending either.
Many patients benefit from both
Profhilo and dermal filler address different layers and can complement each other in the same treatment plan.
Filler restores the structural scaffold in specific zones. Profhilo then improves the quality of the skin sitting above it. These are not competing treatments: they address different things and are often used at different points in a programme. Your clinician will advise on timing and sequence based on your priorities and what your assessment shows.
Finding the right fit
Who each treatment suits
Profhilo Skin Booster
- Adults whose main concern is skin quality: crepey texture, dullness or a loss of resilience rather than volume loss
- Those who want improvement across the face, neck or hands without changing their facial shape
- Those in their late thirties and older noticing overall skin deterioration rather than a specific structural change
Dermal Fillers
- Adults with visible volume loss in areas such as the cheeks, temples or mid-face
- Those with etched lines, nasolabial folds or other specific contour concerns they want to address directly
- Those seeking immediate, visible results in a defined area such as the lips, chin or jawline
Common questions
Frequently asked
Is Profhilo a filler?
Which treatment is better for the under-eye area?
Can Profhilo and dermal filler be used together?
How long do results last for each treatment?
Does dermal filler look natural?
Is there a risk of looking 'overdone' with filler?
Are both treatments suitable during pregnancy?
Can Profhilo replace dermal filler?
Is dermal filler reversible?
Explore each treatment
Read the full treatment details
65 London Road, Newark
Still not sure which is right for you?
Your clinician will assess your skin, talk through both options and give you an honest recommendation, including if neither is the right choice. No obligation to proceed.
Medically reviewed by Dr Shahe Boghossian, Medical Consultant, GMC 5204600 . Last reviewed 23 May 2026.
