Treatment comparison
Profhilo Skin Booster vs Dermal Fillers
Profhilo vs dermal filler at The London Road Clinic, Newark. Understand the clinical difference between these two hyaluronic acid injectables and which is right for your concern.
Side by side
At a glance
| Compare | Profhilo Skin Booster | Dermal Fillers |
|---|---|---|
| Product type | High-concentration hyaluronic acid spread across specific bio-remodelling points | Hyaluronic acid gel placed precisely into targeted anatomical areas |
| Primary effect | Improves skin quality, hydration and elasticity across the treated area | Restores volume, supports structure and refines contour in specific zones |
| Changes facial shape | No | Yes, in the areas treated |
| Best for | Crepey, dull or lax skin where the goal is overall quality and resilience | Volume loss, contour imbalance or etched lines in specific areas such as lips, cheeks, chin or jawline |
| Sessions needed | 2 sessions, typically 4 weeks apart | Often a single session; staged treatment where appropriate |
| Downtime | Usually minimal; small injection bumps settle quickly | Usually mild; swelling and tenderness settle over 24 to 48 hours |
| Results timeline | Builds gradually over several weeks | Immediate, with settling and refinement over 1 to 2 weeks |
| Reversibility | HA breaks down naturally over time | HA fillers can be dissolved with hyaluronidase if clinically needed |
| Price from | From £170 | From £240 |
The science
How each treatment works
Profhilo Skin Booster
Profhilo uses high-concentration hyaluronic acid placed in specific bio-remodelling points on the face, neck or hands. Rather than sculpting or adding bulk, the aim is to spread hydration, improve elasticity and rebuild overall skin quality over time. It works especially well for skin that feels crepey, dull or less resilient rather than primarily volume-depleted.
Full Profhilo Skin Booster details →Dermal Fillers
Hyaluronic acid filler is placed precisely into targeted areas of the face to restore volume, support structure and refine contour. HA also attracts water within the tissue, adding a subtle freshness. Product choice, depth and technique are always tailored to the specific area and the result discussed in consultation.
Full Dermal Fillers details →Clinical perspective
Which is right for you?
Profhilo and dermal fillers are both hyaluronic acid injectables, but they are used for fundamentally different goals. Confusing them is common, and the distinction is worth understanding clearly before your consultation. Profhilo is a skin-quality treatment. Its high-concentration HA is placed into specific bio-remodelling points across the face, neck or hands and is designed to spread through the tissue, improving hydration, elasticity and overall skin resilience. It does not add volume or change the shape of the face. The improvement you see is in the quality and tone of the skin itself: it looks and feels more hydrated, healthier and more resilient. It works especially well for skin that feels crepey, dull or less firm, particularly on the lower face, neck and hands where skin quality tends to deteriorate ahead of volume loss. Dermal fillers are placed precisely into specific anatomical zones to restore structure, refine contours or replace lost volume. The results are immediate and visible: fuller cheeks, a more defined jawline, smoother nasolabial folds, or more shapely lips. Product choice, injection depth and technique are all tailored to the specific area and the outcome discussed in consultation. HA fillers can also be dissolved with hyaluronidase if clinically indicated, which is one reason hyaluronic acid remains the gold-standard filler material. If your concern is the quality of your skin rather than its shape or volume, Profhilo is likely the more appropriate starting point. If you are noticing volume loss, visible folds or contour changes that you want to address in a specific area, filler is the more targeted intervention. Many patients benefit from both at different times, and your clinician will help clarify which addresses your primary concern.
Finding the right fit
Who each treatment suits
Profhilo Skin Booster
- Adults whose main concern is skin quality: crepey texture, dullness or a loss of resilience rather than volume loss
- Those who want improvement across the face, neck or hands without changing their facial shape
- Those in their late thirties and older noticing overall skin deterioration rather than a specific structural change
Dermal Fillers
- Adults with visible volume loss in areas such as the cheeks, temples or mid-face
- Those with etched lines, nasolabial folds or other specific contour concerns they want to address directly
- Those seeking immediate, visible results in a defined area such as the lips, chin or jawline
Common questions
Frequently asked
Is Profhilo a filler?
Which treatment is better for the under-eye area?
Can Profhilo and dermal filler be used together?
How long do results last for each treatment?
Does dermal filler look natural?
Is there a risk of looking 'overdone' with filler?
Are both treatments suitable during pregnancy?
Explore each treatment
Read the full treatment details
65 London Road, Newark
Still not sure which is right for you?
Your clinician will assess your skin, talk through both options and give you an honest recommendation, including if neither is the right choice. No obligation to proceed.
Medically reviewed by Dr Shahe Boghossian, Medical Consultant, GMC 5204600 . Last reviewed 23 May 2026.
