Injectables
Profhilo Skin Booster
- Duration
- 30 mins
- Downtime
- Usually minimal. Small bumps, redness or mild tenderness can occur temporarily after treatment.
From £170
Injectable treatment
Profhilo Structura in Newark
A consultation-led injectable for facial volume loss, structural sagging and fat pad deflation, working in the tissue layer beneath the skin to regenerate and firm where structure has been lost.
- Price
- From £350
- Duration
- 45 mins
- Downtime
- Usually minimal. Mild swelling, tenderness or bruising can occur and typically settles within 24 to 72 hours.
- Results
- Initial firmness often noticeable within days of the first session, with the most visible lifting and definition building over 4 to 6 weeks after the second treatment
- Longevity
- Results typically last 6 to 9 months; maintenance is recommended to sustain improvement
The treatment
How Profhilo Structura works
Profhilo Structura uses a thermally stabilised formulation of 90mg of high and low molecular weight hyaluronic acid per 2ml, a notably higher concentration than standard Profhilo. Rather than spreading through the dermis to improve surface skin quality, it is placed via cannula into the superficial fat layer beneath the skin: the adipose tissue responsible for facial contour and structural support. Once in place, it activates fat cells to behave more youthfully, stimulates collagen and elastin production and reorganises the extracellular matrix, restoring firmness and definition from within. The result is a natural structural lift rather than an added or sculpted volume. At The London Road Clinic, Profhilo Structura is particularly relevant for patients who have experienced significant facial fat pad deflation through ageing or rapid weight loss. For those who have lost facial volume as a result of GLP-1 receptor agonist medication, Structura directly addresses the adipose tissue affected, supporting structural restoration without artificial bulk.
What patients notice
What to expect
- Restores structural firmness and definition without adding artificial volume
- Directly targets the fat layer lost through ageing or rapid weight loss
- Higher HA concentration than standard Profhilo (90mg vs 64mg per 2ml)
- Cannula delivery: typically more comfortable than needle injection
- Stimulates collagen and elastin alongside fat pad regeneration
- Particularly suited to GLP-1 medication-related facial fat loss
Before you book
Is this treatment right for you?
Suitable for
- Adults experiencing facial volume loss, midface sagging, cheek deflation, jowling or loss of structural definition, particularly where the concern is structural rather than surface skin-quality driven.
- Those who have experienced significant facial fat pad depletion following rapid weight loss, including patients on GLP-1 receptor agonist medication, where hollowing, sagging and loss of facial contour have developed as a result.
Not suitable for
- Suitability is reviewed at consultation. Treatment is not appropriate during pregnancy or breastfeeding, with active skin infection, known hypersensitivity to hyaluronic acid or where other injectable contraindications apply.
In their own words
"After losing a significant amount of weight my face looked hollow and aged in a way I hadn't anticipated. Profhilo Structura restored the definition and structure I thought I had lost for good." (Representative client experience. Individual results vary.)
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After your appointment
Aftercare
Avoid vigorous exercise, swimming, saunas and extreme heat for 48 hours after treatment. Keep skincare gentle and follow all injectable aftercare guidance from your clinician. Swelling and tenderness typically settle within 24 to 72 hours.
Common questions
Frequently asked about profhilo structura
What is the difference between Profhilo and Profhilo Structura?
Standard Profhilo is a skin-quality treatment that spreads through the dermis to improve hydration, elasticity and glow without changing facial structure. Profhilo Structura is placed deeper, into the superficial fat layer beneath the skin, to regenerate and firm structural tissue. It uses a higher HA concentration (90mg vs 64mg per 2ml) and a cannula rather than a needle. Structura is the appropriate choice where the concern is structural deflation and sagging rather than surface skin quality.
Is Profhilo Structura a filler?
No. Where dermal filler adds volume to a specific area, Profhilo Structura works by activating fat cells in the layer beneath the skin to behave more youthfully and support the structure above. The result is a natural firming and definition, not an added or sculpted volume.
Can Profhilo Structura help with facial changes caused by weight-loss medication?
Yes. Rapid weight loss, including that associated with GLP-1 receptor agonist medication, can significantly deplete the facial fat layer, leaving the face looking hollow, sagging or structurally deflated in ways that are disproportionate to overall body change. Because Profhilo Structura targets the adipose tissue directly, it addresses the specific layer most affected by this type of loss. Your clinician will assess at consultation whether Structura, dermal filler or a combination approach best suits your presentation.
How many sessions will I need?
The standard course is two sessions 30 days apart. Three sessions may be recommended for more advanced structural loss. Maintenance every 6 to 9 months is advised to sustain results.
When will I see results?
Initial firmness is often noticeable within a few days of the first session. The most visible improvement in lifting and structural definition typically develops over 4 to 6 weeks after the second treatment.
How long do results last?
Results typically last 6 to 9 months, after which maintenance treatment is recommended. Individual longevity varies depending on skin condition, degree of volume loss and metabolic rate.
Is the treatment comfortable?
Cannula delivery is typically more comfortable than needle injection. Most people tolerate the treatment well, with mild pressure or discomfort as the cannula is guided through the tissue.
What aftercare is required?
Avoid vigorous exercise, swimming and extreme heat for 48 hours. Keep skincare gentle and follow all aftercare guidance from your clinician. Mild swelling and tenderness typically settle within 24 to 72 hours.
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Ready to find out more?
Your clinician will take the time to understand your concerns, assess your skin and talk through what Profhilo Structura could realistically achieve for you. No obligation to proceed.
Medically reviewed by Dr Shahe Boghossian, Medical Consultant, GMC 5204600 . Last reviewed 21 May 2026.
