The Dermalux LED Face Mask, red light glowing through the eye, nose and mouth openings

NewThe Dermalux LED Face Mask. Free Bio-Renew EGF Drops worth £50 with every mask, while stocks last.

Injectable treatment

Profhilo Structura in Newark

A consultation-led injectable for facial volume loss, structural sagging and fat pad deflation, working in the tissue layer beneath the skin to regenerate and firm where structure has been lost.

Profhilo Structura at The London Road Clinic, Newark
Price
From £350 per session. Standard course two sessions, 30 days apart
Duration
45 mins
Downtime
Usually minimal. Mild swelling, tenderness or bruising can occur and typically settles within 24 to 72 hours.
Results
Initial firmness often noticeable within days of the first session, with the most visible lifting and definition building over 4 to 6 weeks after the second treatment

The treatment

How Profhilo Structura works

Profhilo Structura uses a thermally stabilised formulation of 90mg of high and low molecular weight hyaluronic acid per 2ml, a notably higher concentration than standard Profhilo. Rather than spreading through the dermis to improve surface skin quality, it is placed via cannula into the superficial fat layer beneath the skin: the adipose tissue responsible for facial contour and structural support. Once in place, it activates fat cells to behave more youthfully, stimulates collagen and elastin production and reorganises the extracellular matrix, restoring firmness and definition from within. The result is a natural structural lift rather than an added or sculpted volume. At The London Road Clinic, Profhilo Structura is particularly relevant for patients who have experienced significant facial fat pad deflation through ageing or rapid weight loss. For those who have lost facial volume as a result of GLP-1 receptor agonist medication, Structura directly addresses the adipose tissue affected, supporting structural restoration without artificial bulk.

What patients notice

What to expect

  • Restores structural firmness and definition without adding artificial volume
  • Directly targets the fat layer lost through ageing or rapid weight loss
  • Higher HA concentration than standard Profhilo (90mg vs 64mg per 2ml)
  • Cannula delivery: typically more comfortable than needle injection
  • Stimulates collagen and elastin alongside fat pad regeneration
  • Particularly suited to GLP-1 medication-related facial fat loss

Before you book

Is this treatment right for you?

Suitable for

  • Adults experiencing facial volume loss, midface sagging, cheek deflation, jowling or loss of structural definition, particularly where the concern is structural rather than surface skin-quality driven.
  • Those who have experienced significant facial fat pad depletion following rapid weight loss, including patients on GLP-1 receptor agonist medication, where hollowing, sagging and loss of facial contour have developed as a result.

Not suitable for

  • Suitability is reviewed at consultation. Treatment is not appropriate during pregnancy or breastfeeding, with active skin infection, known hypersensitivity to hyaluronic acid or where other injectable contraindications apply.

In their own words

After losing a significant amount of weight my face looked hollow and aged in a way I hadn't anticipated. Profhilo Structura restored the definition and structure I thought I had lost for good.
Representative client experience

Illustrative of the feedback we receive for this treatment, not a specific patient review. Individual results vary. Read our 1,500+ verified reviews →

After your appointment

Aftercare

Avoid vigorous exercise, swimming, saunas and extreme heat for 48 hours after treatment. Keep skincare gentle and follow all injectable aftercare guidance from your clinician. Swelling and tenderness typically settle within 24 to 72 hours.

From the clinic shop

What we would send you home with

Structura is the firmer, more structural end of the Profhilo range. Two products working on the same thing at the surface, and two for the first few days while swelling and tenderness settle.

  • Dermalux LED Face Mask

    Device

    Dermalux LED Face Mask

    At-home LED from Dermalux, whose Tri-Wave and Flex units we use in clinic. Built to hold a result between appointments across a Structura course.

    £449.00 Buy now
  • Phyto-Active Firming Serum 30 ml

    Skincare

    Phyto-Active Firming Serum 30 ml

    Plant stem cells and a multi-peptide complex, the firming serum in the range. For daily use once the injection sites have settled.

    £152.00 Buy now
  • Oil Free SPF 40+ 50 ml

    Skincare

    Oil Free SPF 40+ 50 ml

    Broad-spectrum 40+ every day. Sun damage works against firmness faster than any serum works for it.

    £52.00 Buy now
  • HD Mineral Foundation Stick

    Beauty

    HD Mineral Foundation Stick

    A stick base with hyaluronic acid and an antioxidant complex, twelve shades. Precise enough to place over a spot of bruising rather than over the whole face.

Prices are shown as they stand on our retail store and are confirmed at checkout. Product choice is a suggestion, not part of your treatment plan: your clinician's aftercare advice above comes first.

Where Structura sits

Structura is the one I explain most often, because it sits between two things people already know. It is not standard Profhilo and it is not filler. It goes into the fat layer beneath the skin, which is the layer that thins with age and thins fastest with weight loss. If you have lost a lot of weight and your face has hollowed before the rest of you caught up, this is the conversation to have.

Lydia Griffin, Clinic Director

Two visits, then twice a year at most

The clinic is at 65 London Road, Newark-on-Trent, NG24 1RZ, with free parking at the front.

Two sessions thirty days apart, then maintenance every six to nine months. So the demanding part is a single month, and after that this is one of the lowest-frequency treatments we offer. Worth knowing if you are weighing it against something that needs you here every week.

Newark is well connected by the A1 and A46, so the clinic is within easy reach of Southwell, Bingham, Bottesford and Radcliffe on Trent, as well as Lincoln, Grantham, Sleaford and West Bridgford.

Book the second appointment before you leave the first. Thirty days is the interval the plan is built on and it holds better when it is already in the diary.

Further reading: Profhilo Structura across Nottinghamshire, what causes facial volume loss, and the jawline and jowls. Background on the concern: volume loss.

Local pages for this treatment: West Bridgford and Southwell.

Common questions

Frequently asked about Profhilo Structura

What is the difference between Profhilo and Profhilo Structura?
Standard Profhilo is a skin-quality treatment that spreads through the dermis to improve hydration, elasticity and glow without changing facial structure. Profhilo Structura is placed deeper, into the superficial fat layer beneath the skin, to regenerate and firm structural tissue. It uses a higher HA concentration (90mg vs 64mg per 2ml) and a cannula rather than a needle. Structura is the appropriate choice where the concern is structural deflation and sagging rather than surface skin quality.
Is Profhilo Structura a filler?
No. Where dermal filler adds volume to a specific area, Profhilo Structura works by activating fat cells in the layer beneath the skin to behave more youthfully and support the structure above. The result is a natural firming and definition, not an added or sculpted volume.
Can Profhilo Structura help with facial changes caused by weight-loss medication?
Yes. Rapid weight loss, including that associated with GLP-1 receptor agonist medication, can significantly deplete the facial fat layer, leaving the face looking hollow, sagging or structurally deflated in ways that are disproportionate to overall body change. Because Profhilo Structura targets the adipose tissue directly, it addresses the specific layer most affected by this type of loss. Your clinician will assess at consultation whether Structura, dermal filler or a combination approach best suits your presentation.
How many sessions will I need?
The standard course is two sessions 30 days apart. Three sessions may be recommended for more advanced structural loss. Maintenance every 6 to 9 months is advised to sustain results.
When will I see results?
Initial firmness is often noticeable within a few days of the first session. The most visible improvement in lifting and structural definition typically develops over 4 to 6 weeks after the second treatment.
How long do results last?
Results typically last 6 to 9 months, after which maintenance treatment is recommended. Individual longevity varies depending on skin condition, degree of volume loss and metabolic rate.
Is the treatment comfortable?
Cannula delivery is typically more comfortable than needle injection. Most people tolerate the treatment well, with mild pressure or discomfort as the cannula is guided through the tissue.
What aftercare is required?
Avoid vigorous exercise, swimming and extreme heat for 48 hours. Keep skincare gentle and follow all aftercare guidance from your clinician. Mild swelling and tenderness typically settle within 24 to 72 hours.

You may also want to explore

Related treatments

Related reading

Compare your options

Medically reviewed by Dr Shahe Boghossian, Medical Consultant, GMC 5204600. Last reviewed 5 Aug 2026. Page updated 16 Aug 2026.

65 London Road, Newark

Ready to find out more?

Your clinician will take the time to understand your concerns, assess your skin and talk through what Profhilo Structura could realistically achieve for you. No obligation to proceed.

Registered with & recognised by

Book a consultation WhatsApp